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PulseNet China, a model for future laboratory-based bacterial infectious disease surveillance in China

Wei Li, Shan Lu, Zhigang Cui, Jinghua Cui, Haijian Zhou, Yiqing Wang, Zhujun Shao, Changyun Ye, Biao Kan, Jianguo Xu

Frontiers of Medicine 2012, Volume 6, Issue 4,   Pages 366-375 doi: 10.1007/s11684-012-0214-6

Abstract:

Surveillance is critical for the prevention and control of infectious disease.China’s real-time web-based infectious disease reporting system is a distinguished achievement.However, many aspects of the current China Infectious Disease Surveillance System do not yet meet thedemand for timely outbreak detection and identification of emerging infectious disease.PulseNet to develop a model for a future national laboratory-based surveillance system for all bacterial infectious

Keywords： infectious disease     laboratory-based infectious disease surveillance     pulse field gel electrophoresis     multilocus    

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Toll-like receptors in innate immunity and infectious diseases

Min-Hao WU, Ping ZHANG, Xi HUANG,

Frontiers of Medicine 2010, Volume 4, Issue 4,   Pages 385-393 doi: 10.1007/s11684-010-0600-x

Abstract: TLRs in the innate immune system have implications for the prevention and treatment of a variety of infectious

Keywords： Toll-like receptors     innate immunity     infectious disease     inflammation    

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Responses to emerging and re-emerging infectious diseases: One world, One health

Jianqing Xu, Jianguo Xu

Frontiers of Medicine 2018, Volume 12, Issue 1,   Pages 1-2 doi: 10.1007/s11684-018-0619-y

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Passive antibody therapy in emerging infectious diseases

Frontiers of Medicine doi: 10.1007/s11684-023-1021-y

Abstract: antibody therapy against VOCs was assessed, offering insights into the coping strategies for facing new infectious

Keywords： SARS-CoV-2     COVID-19     convalescent plasma     hyperimmunoglobulin     neutralizing monoclonal antibodies    

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Landscape of emerging and re-emerging infectious diseases in China: impact of ecology, climate, and behavior

Qiyong Liu, Wenbo Xu, Shan Lu, Jiafu Jiang, Jieping Zhou, Zhujun Shao, Xiaobo Liu, Lei Xu, Yanwen Xiong, Han Zheng, Sun Jin, Hai Jiang, Wuchun Cao, Jianguo Xu

Frontiers of Medicine 2018, Volume 12, Issue 1,   Pages 3-22 doi: 10.1007/s11684-017-0605-9

Abstract:

For the past several decades, the infectious disease profile in China has been shifting with rapidNotably, 5 notifiable infectious diseases have been almost eradicated, and the incidence of 18 additionalnotifiable infectious diseases has been significantly reduced.Nevertheless, frequent infectious disease outbreaks/events have been reported almost every year, andimported infectious diseases have increased since 2015.

Keywords： infectious disease profile     emerging infectious diseases     influence factor    

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triggering receptor expressed on myeloid cell-1 (sTREM-1): a potential biomarker for the diagnosis of infectious

Changlin Cao, Jingxian Gu, Jingyao Zhang

Frontiers of Medicine 2017, Volume 11, Issue 2,   Pages 169-177 doi: 10.1007/s11684-017-0505-z

Abstract: Sensitive and useful biomarkers for the diagnosis and prognosis of infectious diseases have been widelyspecial form of TREM-1 that can be directly tested in human body fluids and well-known biomarker for infectiousdiseases, including infectious pleural effusion, lung infections, sepsis, bacterial meningitis, viralbiomarker than traditional indices, such as C-reactive protein and procalcitonin levels, for these infectiousTherefore, sTREM-1 is a feasible biomarker for the targeted therapy and rapid and early diagnosis of infectious

Keywords： soluble triggering receptor expressed on myeloid cells-1     infectious diseases     diagnosis and prognosis    

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Facilities for Centralized Isolation and Quarantine for the Observation and Treatment of Patients with Article

Xianliang Wang, Jiao Wang, Jin Shen, John S. Ji, Lijun Pan, Hang Liu, Kangfeng Zhao, Li Li, Bo Ying, Lin Fan, Liubo Zhang, Lin Wang, Xiaoming Shi

Engineering 2021, Volume 7, Issue 7,   Pages 908-913 doi: 10.1016/j.eng.2021.03.010

Abstract:

The coronavirus disease 2019 (COVID-19) pandemic increased the burden on many healthcare systems and in the process, exposed the need for medical resources and physical space. While few studies discussed the efficient utilization of medical resources and physical space so far. Therefore, this study aimed to summarize experiences related to facilities used for centralized isolation for medical observation and
treatment during the COVID-19 pandemic in China and to provide suggestions to further improve the management of confirmed cases, suspected cases, and close contacts. In China, three types of facilities for centralized isolation (Fangcang shelter hospitals, refitted non-designated hospitals, and quarantine hotels) underwent retrofitting for the treatment and isolation of confirmed and suspected cases. These
facilities mitigated the immediate high demand for space. Moreover, in order to minimize infection risks in these facilities, regulators and governmental agencies implemented new designs, management measures, and precautionary measures to minimize infection risk. Other countries and regions could refer to China’s experience in optimally allocating social resources in response to the COVID-19 pandemic.
As a conclusion, government should allocate social resources and construct centralized isolation and quarantine facilities for an emergency response, health authorities should issue regulations for centralized isolation facilities and pay strict attention to the daily management of these facilities, a multidisciplinary administration team is required to support the daily operation of a centralized isolation facility, in-depth studies and international collaboration on the centralized isolation policy are encouraged.

Keywords： Centralized isolation     Risk control     Infectious patients     Close contacts     Coronavirus disease    

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Unusual global outbreak of monkeypox: what should we do?

Frontiers of Medicine 2022, Volume 16, Issue 4,   Pages 507-517 doi: 10.1007/s11684-022-0952-z

Abstract: Recently, monkeypox has become a global concern amid the ongoing COVID-19 pandemic. Monkeypox is an acute rash zoonosis caused by the monkeypox virus, which was previously concentrated in Africa. The re-emergence of this pathogen seems unusual on account of outbreaks in multiple nonendemic countries and the incline to spread from person to person. We need to revisit this virus to prevent the epidemic from getting worse. In this review, we comprehensively summarize studies on monkeypox, including its epidemiology, biological characteristics, pathogenesis, and clinical characteristics, as well as therapeutics and vaccines, highlighting its unusual outbreak attributed to the transformation of transmission. We also analyze the present situation and put forward countermeasures from both clinical and scientific research to address it.

Keywords： monkeypox     poxviruses     vaccine     infectious diseases    

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Nucleic acid-based diagnostics for infectious diseases in public health affairs

Albert Cheung-Hoi Yu, Greg Vatcher, Xin Yue, Yan Dong, Mao Hua Li, Patrick H. K. Tam, Parker Y.L. Tsang, April K.Y. Wong, Michael H.K. Hui, Bin Yang, Hao Tang, Lok-Ting Lau

Frontiers of Medicine 2012, Volume 6, Issue 2,   Pages 173-186 doi: 10.1007/s11684-012-0195-5

Abstract:

Infectious diseases, mostly caused by bacteria and viruses but also a result of fungal and parasitic

Keywords： nucleic acid-based diagnostics     infectious disease     PCR     NASBA     LAMP     microarray     LOAC     public health affairs    

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A comprehensive information database (CID) of breast cancer patients in China

Shuai Li, Li Fu

Frontiers of Medicine 2012, Volume 6, Issue 2,   Pages 212-216 doi: 10.1007/s11684-012-0185-7

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Reliability of foam posturography in assessment of postural balance in the patients with vertigo

LIU Bo, KONG Weijia

Frontiers of Medicine 2008, Volume 2, Issue 4,   Pages 361-365 doi: 10.1007/s11684-008-0069-z

Abstract: To our knowledge, there is no report about the test-retest reliability of foam posturography in the patientsThe foam posturography was taken on the patients with vertigo in stable state and repeated in 3 to 5The results of patients with vertigo were compared with those of normal subjects.There were 10 of 34 patients with vertigo at least fell one time during the two assessments, and the(1) The interclass correlation coefficients (ICC) of all 49 subjects including normal subjects and patients
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Efficacy and safety of JAK inhibitor INC424 in patients with primary and post-polycythemia vera or post-essential

Xin Du,Daobin Zhou

Frontiers of Medicine 2016, Volume 10, Issue 4,   Pages 437-443 doi: 10.1007/s11684-016-0472-9

Abstract: A2202) was performed to evaluate the efficacy and safety of JAK inhibitor ruxolitinib in 63 Chinese MF patientsAbout 94.7% of the patients achieved a reduction in spleen size, 27.0% of which exhibited significantSignificant improvement in debilitating constitutional symptoms, as assessed by MFSAF v2.0, was observed in patientsRuxolitinib treatment was generally well tolerated by Chinese patients.substantial reductions in splenomegaly and improvements in symptoms, and was well-tolerated by Chinese patients

Keywords： JAK     ruxolitinib     Chinese patients     myelofibrosis    

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Translating the power of TCM into patients’ hope

Guangbiao Zhou,Zhu Chen

Frontiers of Medicine 2014, Volume 8, Issue 3,   Pages 265-267 doi: 10.1007/s11684-014-0329-z

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Hypertension in patients with CKD in China: clinical characteristics and management

Guangyan Cai, Xiangmei Chen

Frontiers of Medicine 2017, Volume 11, Issue 3,   Pages 307-309 doi: 10.1007/s11684-017-0578-8

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Health: a dream from reality to the future

Chunsong Hu,Qinghua Wu

Frontiers of Medicine 2016, Volume 10, Issue 2,   Pages 233-235 doi: 10.1007/s11684-016-0444-0

Abstract:

This paper argues that health is a realistic productive force that may enhance the index of happiness. As the basis of all developments and the source of a person’s and his/her family’s happiness, health requires not only primary and secondary prevention, but also policy prevention, that is to say, grade-zero prevention. Therefore, people should pay more attention to Health in All Policies. As a new preventive strategy, the policy prevention will help improve people’s health significantly and promote the concepts of “Healthy China” and “the Chinese Dream” or “the World Dream” to realize a dream from reality to the future.

Keywords： health promotion     primary and secondary prevention     policy prevention     infectious disease     non-communicable    

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Title Author Date Type Operation

PulseNet China, a model for future laboratory-based bacterial infectious disease surveillance in China

Wei Li, Shan Lu, Zhigang Cui, Jinghua Cui, Haijian Zhou, Yiqing Wang, Zhujun Shao, Changyun Ye, Biao Kan, Jianguo Xu

Journal Article

Toll-like receptors in innate immunity and infectious diseases

Min-Hao WU, Ping ZHANG, Xi HUANG,

Journal Article

Responses to emerging and re-emerging infectious diseases: One world, One health

Jianqing Xu, Jianguo Xu

Journal Article

Passive antibody therapy in emerging infectious diseases

Journal Article

Landscape of emerging and re-emerging infectious diseases in China: impact of ecology, climate, and behavior

Qiyong Liu, Wenbo Xu, Shan Lu, Jiafu Jiang, Jieping Zhou, Zhujun Shao, Xiaobo Liu, Lei Xu, Yanwen Xiong, Han Zheng, Sun Jin, Hai Jiang, Wuchun Cao, Jianguo Xu

Journal Article

triggering receptor expressed on myeloid cell-1 (sTREM-1): a potential biomarker for the diagnosis of infectious

Changlin Cao, Jingxian Gu, Jingyao Zhang

Journal Article

Facilities for Centralized Isolation and Quarantine for the Observation and Treatment of Patients with

Xianliang Wang, Jiao Wang, Jin Shen, John S. Ji, Lijun Pan, Hang Liu, Kangfeng Zhao, Li Li, Bo Ying, Lin Fan, Liubo Zhang, Lin Wang, Xiaoming Shi

Journal Article

Unusual global outbreak of monkeypox: what should we do?

Journal Article

Nucleic acid-based diagnostics for infectious diseases in public health affairs

Albert Cheung-Hoi Yu, Greg Vatcher, Xin Yue, Yan Dong, Mao Hua Li, Patrick H. K. Tam, Parker Y.L. Tsang, April K.Y. Wong, Michael H.K. Hui, Bin Yang, Hao Tang, Lok-Ting Lau

Journal Article

A comprehensive information database (CID) of breast cancer patients in China

Shuai Li, Li Fu

Journal Article

Reliability of foam posturography in assessment of postural balance in the patients with vertigo

LIU Bo, KONG Weijia

Journal Article

Efficacy and safety of JAK inhibitor INC424 in patients with primary and post-polycythemia vera or post-essential

Xin Du,Daobin Zhou

Journal Article

Translating the power of TCM into patients’ hope

Guangbiao Zhou,Zhu Chen

Journal Article

Hypertension in patients with CKD in China: clinical characteristics and management

Guangyan Cai, Xiangmei Chen

Journal Article

Health: a dream from reality to the future

Chunsong Hu,Qinghua Wu

Journal Article